Transcranial magnetic stimulation (TMS) is a game-changer for anyone struggling with treatment-resistant depression. While highly effective, TMS can also require a considerable amount of time.
A standard TMS treatment requires patients to attend daily weekday sessions over nine weeks, with each session lasting 20 to 40 minutes.
Thanks to new TMS technology, treatment is now faster and even more efficient. Today, accelerated TMS has shortened treatment to just one week. Plus, research shows it caused remission in nearly 80% of participants.
What is accelerated TMS?
TMS is a non-surgical treatment that uses a series of repetitive magnetic pulses to “wake up” underactive nerve cells in the areas of the brain that control mood. Over time, TMS can build neuroplasticity in the brain by strengthening and establishing new neural pathways and connections.
Cleared by the US Food and Drug Administration in 2008, TMS is approved to treat:
- Major depressive disorder
- Treatment-resistant depression
- Anxious depression
- Obsessive-compulsive disorder (OCD)
- Smoking cessation
- Migraines with aura
TMS technology advanced in the early 2000s with the development of theta burst stimulation (TBS.) Also known as Express TMS, this protocol was designed to mimic theta rhythms, a brain state linked to learning that is the most receptive to change.
By following this natural rhythm, Express TMS encourages the brain to form new connections more efficiently while supporting neuroplasticity, the brain’s ability to adapt and heal.
This efficiency means Express TMS can shorten treatment sessions to just 3-4 minutes, all while being just as effective as standard 20-40 minute TMS sessions.
The success of Express TMS led researchers at Stanford University to develop the SAINT protocol, an accelerated TMS treatment where patients receive up to 10 sessions a day for five days. Functional brain imaging can also be used to target the exact brain region to stimulate for each person, making treatment even more personalized and effective.
The goal for the SAINT protocol was to improve outcomes and shorten the treatment timeline for patients with treatment-resistant depression, a form of depression that does not improve from medications or therapy.
Is accelerated TMS right for you
A provider will conduct a clinical evaluation and work with patients to determine the right TMS treatment protocol to meet their needs, personal preference, and insurance coverage.
Pacific Mind Health offers three types of TMS. Here’s what to expect for each one:
Standard TMS
- 20- to 40-minute daily weekday sessions over nine weeks
- Best for patients who can commit to a longer course of treatment
Express TMS
- 3- to 4-minute daily weekday sessions over nine weeks
- Ideal for working professionals or caregivers with limited time
Accelerated TMS
- Up to 10 daily 3- to 4-minute sessions over just five days
- Best for patients who can tolerate long treatment days, need fast results, or have limited long-term availability
All three treatment protocols produce similar results, although accelerated TMS is likely to provide faster results. Some patients may feel noticeable relief within days, while others may see gradual improvement over one to two weeks after treatment.
Maintenance sessions may be recommended in the weeks or months following treatment to help sustain symptom relief. Providers will personalize this based on their patient’s progress.
Accelerated TMS: what to expect
Any TMS treatment begins with a brain mapping session to identify the right spot to deliver treatment and determine the strength needed for stimulation.
Accelerated TMS is a more intensive treatment format than the Standard or Express options. Each day, patients receive multiple short TMS sessions spaced about 50 minutes apart, typically totaling 6 to 10 sessions per day. The treatment day usually lasts 6 to 8 hours.
Some people describe the sensation of TMS as a light tapping or clicking on the scalp. While mild discomfort or muscle twitching can occur at first, these effects usually lessen over time.
Between accelerated TMS sessions, patients have time to rest, eat, take breaks, or do light activities like reading or listening to music. Many bring snacks, water, a book, or something comforting to help them relax between sessions.
Most patients can drive themselves to and from treatment and return to regular activities right after treatment.
While accelerated TMS is well tolerated, it can be mentally and physically tiring due to the condensed schedule. Some patients may experience fatigue or emotional ups and downs during the week. It’s important to have flexibility in your schedule and support at home if needed.
Risks and side effects
Like any treatment, accelerated TMS may have some side effects, although these are generally mild, temporary, and well tolerated.
The most common side effects include:
- Scalp discomfort at the treatment site
- Headache
Less common side effects can include:
- Fatigue or drowsiness
- Lightheadedness
Rare but serious side effects can include:
- Seizures, although the possibility is less than 0.1%
Side effects typically improve as the brain adjusts to stimulation. Breaks between sessions can help reduce intensity. Because TMS does not involve medication, patients avoid the systemic side effects, such as weight gain, commonly associated with antidepressants.
Summary
Accelerated TMS is a powerful new approach for people with treatment-resistant depression. While traditional TMS takes several weeks, this method condenses treatment into just five days, often with faster results.
Key takeaways
- Accelerated TMS delivers up to 10 daily sessions over five days, offering a faster alternative to standard TMS therapy.
- It uses theta burst stimulation (TBS) to mimic natural brain rhythms, supporting neuroplasticity and mood regulation.
- Research shows up to 80% remission rates in clinical trials for treatment-resistant depression.
- Patients typically tolerate treatment well, with mild and temporary side effects such as scalp discomfort or fatigue.
- Pacific Mind Health offers three TMS options — standard, Express, and accelerated — to match your lifestyle and clinical needs.
Looking for TMS treatment near you?
Pacific Mind Health offers transcranial magnetic stimulation (TMS) for depression, OCD, and other mental health conditions. Our experienced clinicians provide compassionate, evidence-based care to help you feel better.
Ready to take the next step? Schedule a free consultation today to see if TMS is right for you.
