What is SPRAVATO?

Progress in the field of mental health care has brought renewed hope to those facing severe and treatment-resistant depression. A noteworthy development in this realm is the introduction of SPRAVATO, a medication designed to address depression symptoms in an innovative way. Also known as esketamine, SPRAVATO offers a fresh option for individuals who have not found relief with standard treatments. Keep reading to learn more about this breakthrough medication.

What is SPRAVATO?

SPRAVATO is a medication containing esketamine used to treat depression in cases where traditional antidepressants have not been effective. It marks a step in managing severe depressive disorders by offering new hope to patients.

Esketamine is derived from ketamine, an anesthetic. Researchers observed esketamine’s antidepressant properties, leading to the development of esketamine as a focused treatment for depression. The FDA approval of SPRAVATO in March 2019 for adults with treatment-resistant depression was an important moment in depression treatment. Extensive clinical trials supported the medication’s effectiveness and safety profile for individuals who did not benefit from two or more antidepressants.

How Does Spravato Work?

When it comes to antidepressants like SSRIs and SNRIs, their mechanism involves altering the levels of serotonin and norepinephrine in the brain. For instance, SSRIs block serotonin reuptake, increasing its presence over time, leading to an uplifting mood. On the other hand, SNRIs inhibit both serotonin and norepinephrine reuptake. These medications usually take a few weeks to show effects as they gradually modify neurotransmitter systems and brain function.

In contrast, SPRAVATO acts swiftly by targeting a separate system in the brain. By targeting this separate mechanism, SPRAVATO can have an immediate impact, which is advantageous for individuals struggling with depression who haven’t found relief through slow-activation traditional  treatments. This quicker response aids in symptom alleviation. 

Various clinical trials have underscored the benefits of SPRAVATO and highlighted its effectiveness in treating depression for those who haven’t found symptom relief from other treatment methods. Studies reveal that esketamine has alleviated symptoms when compared to a placebo, especially among patients unresponsive to other antidepressant therapies. 

Who Can Reap the Benefits of SPRAVATO?

When traditional treatments for depression prove ineffective, individuals may be diagnosed with treatment-resistant depression (TRD). Those with TRD have usually tried antidepressant medications without finding relief from their symptoms. Managing this type of depression can have an impact on a person’s daily life. SPRAVATO presents an option for these individuals struggling with TRD. It can be beneficial for those who have not responded well to prescribed antidepressants like SSRIs or SNRIs. The unique way in which SPRAVATO works makes it an appealing alternative for these individuals, offering hope when other treatments have fallen short.

However, SPRAVATO does have a risk of misuse. Due to its resemblance to ketamine chemically, there is a risk of misuse or abuse. Therefore, SPRAVATO is administered under the supervision of a healthcare provider in controlled settings.

In essence, SPRAVATO brings hope to individuals with treatment-resistant depression who have not responded well to other kinds of treatment. To be eligible for SPRAVATO, a person must have a diagnosis of a depressive disorder and have previously tried antidepressants without success. 

Find SPRAVATO Treatment at Pacific Mind Health

SPRAVATO is a breakthrough in treating depression for those with treatment-resistant depression. In today’s fast-paced world it is more important than to prioritize mental health. Pacific Mind Health shines as a beacon of hope and support for individuals on their mental health journeys. Pacific Mind Health is a psychiatry center that specializes in providing this cutting-edge medication. Our tailored treatment programs combine SPRAVATO with other evidence-based methods for a holistic approach to care. 

Pacific Mind Health is dedicated to helping patients make significant and long-lasting improvements in their mental well-being. An on-site team of professionals who are deeply passionate about mental health creates an environment where clients can find understanding, support and the resources necessary to lead fulfilling lives.

If you or someone you know is battling depression, Pacific Mind Health is committed to assisting individuals through their recovery journey by offering guidance and treatment plans tailored to their needs. Taking the step to seek assistance is critical to finding relief and enhancing quality of life. Pacific Mind Health stands ready to guide you through this process. Contact us to find a treatment center location near you.